General and specialized histology, immunohistochemistry, TMA’s, special stains
The Rosalind and Morris Goodman Cancer Research Centre has established a specialized histology service to respond to the needs of its members, as well as investigators from outside the McGill research community. These services focus on research needs related to tumour-tissue characterization for cancer-related projects, developmental histology (embryos) and animal pathology. The samples submitted for analysis are treated with the highest standards in quality, using the latest technological advances. Coupled with assessments by a veterinary pathologist, Dr. Jean-Martin Lapointe (DMV, MS, dACVP), the services provided by the centre’s Histology Core Facility ensure that submitted projects benefit from a combination of high technical quality, rapid sample processing and unique pathology expertise.
The Histology Core Facility is a full-service research facility providing a wide range of services for routine histological procedures, including:
- Tissue processing for paraffin/frozen blocks
- Sectioning of paraffin/frozen blocks
- H&E and a variety of special stains for paraffin and frozen sections
- Training in general tissue processing and histology study methodologies
- Immunohistochemistry
- TMA’s
- Histology
- Immunohistochemistry
- TMA’s
- Agriculture, animal science and food
- Education
- Healthcare and social services
Specialized labs and equipment
Equipment |
Function |
---|---|
Sakura Tissue-Tek VIP tissue processor |
Processing tissue |
Leica EG1150 H embedder |
Embedding tissue samples |
Leica ST5020 stainer |
Automated stainer |
Leica CV5030 |
Automated cover slipper |
IntelliPath |
Automated Immunohistochemistry stainer |
Beecher TMA |
TMA arrayer |
Leica, Microm and Shandon microtomes |
Automated and manual microtomes to cut tissue samples embedded in paraffin |
Microm and Fisher cryostats |
Cutting frozen samples |
SlideMate |
Slide labeller |
Private and public sector research partners
- University of Calgary
- Université de Montréal
- Royal Victoria Hospital
- Montreal General Hospital
- Montreal Children’s Hospital
- Shriner’s Hospital
- McGill University Hospital Centre Research Institute