Study of the pathogeny of infectious diseases in animals
The transmission electron microscopy laboratory provides services for virus identification and visualization of pathogenic microorganisms primarily affecting animals as well as some that are zoonotic, that is, that can also affect humans. In addition, our laboratory specializes in the study of co-infections and interactions that may exist between pathogens themselves (pathogen-pathogen interactions, for example, porcine reproductive and respiratory syndrome virus (PRRSV) with Actinobacillus pleuropneumoniae) and the effects that pathogens may have on the infected animal. Depending on the pathogen-pathogen interactions we identify, some interactions significantly increase the virulence of a pathogen (synergistic effect), while other interactions significantly decrease the virulence of a given pathogen (antagonistic effect). The transmission electron microscopy lab is also used to identify the structures that make up the surface of pathogenic bacteria in animals such as Streptococcus suis and Clostridium perfringens and pathogenic viruses in animals such as PRRSV and porcine epidemic diarrhea virus (PEDV).
Electron microscopy is a technique used to visualize very small objects like viruses or cell compartments. An electron beam is transmitted through a very thin sample, which is deposited on a grid. The interactions between the electrons and the sample generate the image, the resolution of which can reach 0.08 nanometres.
- Agriculture, animal science and food
- Life sciences, pharmaceuticals and medical equipment
Specialized Labs and Equipment
Name of equipment in use
Description of function
Transmission electron microscope (Hitachi)
Visualization of infectious nanoparticles (viruses, bacteria) and synthesis
Private and Public Sector Research Partners
- Genome Alberta
- Génome Québec
- the Quebec Ministry of Agriculture/Fisheries and Food
- the Fédération des producteurs de porcs du Québec (Quebec hog farming federation)