Sherbrooke Molecular Imaging Centre (CIMS)

Université de Sherbrooke, Sherbrooke, Québec
What the facility does

Preclinical imaging platform (PET, CT, MRI, optical), radiochemistry and development of new imaging technologies

Areas of expertise

The Sherbrooke Molecular Imaging Centre (CIMS) of the Sherbrooke University Hospital Research Centre (CRCHUS) provides researchers and the industry with a unique range of preclinical and clinical imaging technologies. It has recognized expertise in positron emission tomography (PET), X-ray computed tomography (CT), magnetic resonance imaging (MRI) and optical imaging. With two cyclotrons and its radiochemistry service, the centre offers a wide range of radiotracers (C-11, N-13, F-18, Cu-64, Tc-99m) and radiopharmaceuticals (FDG, FTHA, acetate, acetoacetate, carvedilol, PIB). The centre’s laboratories are also actively involved in developing new preclinical imagers and new pharmaceutical agents for preclinical and clinical imaging (radiotracers, contrast mediums and optical probes). The centre has all of the infrastructure required for in vitro and in vivo validation (in animals and in clinical environments). Its clinical work serves a large population, and it is actively involved in research on oncology, cardiology, metabolism and neurology.

Research services

Our research expertise focuses on both animals and humans:

  • Radiochemistry service that offers biomolecule labelling with different radiotracers. Measurement of the in vitro and in vivo stability of radiopharmaceuticals including biodistribution studies.
  • Preclinical and clinical imaging (PET, SPECT, CT, MRI and optical imaging).
  • Monitoring of cardiac function and metabolism by PET/CT/MRI. Cerebral imaging. Therapeutic monitoring in murine and xenograft cancer models. Imaging assessments of new drugs.
  • Pharmacokinetics analysis and image processing service using an image analysis and visualization platform.
  • Animal facilities for housing small- and medium-sized animals on location.
  • Instrumentation and engineering component that works on developing new scanners and medical devices.
Sectors of application
  • Education
  • Healthcare and social services
  • Life sciences, pharmaceuticals and medical equipment
Specialized labEquipmentFunction
Preclinical imagingTriumph™ 8 cm PET/SPECT/CTFunctional and anatomical imaging of small animals
 LabPET™ 4 cm PETFunctional imaging of small animals
 LabPET™ II PET/SPECTFunctional and anatomical imaging of small animals
 Optima™ SPECTFunctional imaging of big and small animals
 Varian™ 7 t MRIMagnetic resonance imaging of small animals
 QOS™ optical imagerFunctional and anatomical imaging of small animals
 Hidex Automatic Gamma CounterBiodistribution analysis
Preclinical servicesAnimal facilities with ventilated carriers (Level II certified)Housing on site
 SAITA 3Digital animal files
Clinical imagingPhilips™ Gemini GXLFunctional and anatomical imaging of humans
 Philips™ Gemini TFFunctional and anatomical imaging of humans
 Philips™ Ingenia 3 t MRIMagnetic resonance imaging of humans
 Siemens™ 1.5 t MRIMagnetic resonance imaging of humans
CyclotronsEBCO/ACSI TR-19Production of radioisotopes
 ACSI TR-24Production of radioisotopes
Radiochemistry3 clean roomsHealth Canada certifications
 Radiosynthesis units 
 Hot cells 
 Quality control laboratory 
 Analytical equipment (HPLC, UPLC, MS) 
 Organic chemistry laboratory 
InstrumentationComputer clusterImage reconstruction and processing
 PET/SPECT scanner simulatorsScanner development
 Instrumentation laboratoryDesign of detectors, scanners and medical devices
 Mechanical workshop 
  • Charles River Laboratories Inc.
  • iPST
  • Medtronic
  • AngioTox (EU-FP7)
  • Université de Montréal
  • Montreal Heart Institute
  • Institut universitaire de cardiologie et de pneumologie de Québec
Research... fundamental for health | Au coeur de la vie 2014
Manning Innovation Awards 2012