Centre for Heart Lung Innovation (HLI)

The University of British Columbia, Vancouver, British Columbia
What the facility does

Cardiovascular and pulmonary

Area(s) of Expertise

Basic and clinician scientists work together in an exciting multidisciplinary environment to address vital issues in heart, lung and critical-care disease. Situated within Providence Health Care’s St. Paul’s Hospital, a University of British Columbia teaching hospital, the HLI is a translational research centre using our basic molecular and cellular research discoveries to develop innovative approaches to prevent and treat human disease through our complementary and connected clinical research.

Our focus is on developing solutions to the biggest challenges: atherosclerosis and heart failure, emphysema and other chronic pulmonary diseases, severe infections and multiple-organ failure, at the cellular, preclinical and clinical levels.

Research Services

microscopy, Imaging, pathology and morphology, preclinical in vivo, histology, molecular phenotyping

Sectors of Application
  • Life sciences, pharmaceuticals and medical equipment

Name of specialized lab

Name of equipment

Description of function

Microscopy/imaging

Multiphoton, confocal, electron microscope

Atomic force microscope

Structured illumination microscopy

Aperio slide scanning

Dissecting microscope with digital camera

Laser capture micro-dissection for DNA and RNA

Single-cell fluorescence microscope

Micro CT scanner

Our microscopy services support the centre's educational and research missions. We provide services to individual institutions and private industry in ultra-high-resolution imaging of cells and tissues in fixed and living specimens. In addition, we provide services in image analysis. 

Histology

Tissue processors

Cryostats

RX Bond autostainer

Our histology core offers a wide range of quality histological services delivered by experienced technicians who can work with you to advise on the best applications

Molecular Phenotyping Laboratory

Flow cytometry

PCR

Mass spectrometer

Luminex

Cell sorter

Cytocentrifuge

Biorepository services

This multi-user facility has an extensive range of equipment tailored to the phenotyping of patients, experimental animal models, tissues, cells and molecules

GEM Preclinical Facility

Visualsonics ultrasound for rodents

Telemetry

Surgical microscopy

Anaesthesia

Harvard voluntary wheel running system

Kent Scientific non-invasive blood pressure monitoring

Millar catheter system

Our facility offers flexible space, tech services and equipment for use with rodent and rabbit models. It contains a barrier breeding unit, a level-2 containment suite and conventional and surgical areas. As part of a network of service providers with the BC PRC (www.bcprc.com), we can work with you to achieve your research goals or manage your project for you.