Neurobiology research on stress, using various molecular, cellular and neurophysiological techniques
The Centre for the Neurobiology of Stress (CNS) is a $10-million state-of-the-art facility. The centre tackles a series of critical areas: long-term memory and consolidation; the role of stress in natural population; maternal effects and maternal programming through epigenetic changes; neuroprotective roles of heat shock (stress) proteins; neurobiology and behaviour using fear, addiction, and other paradigms to understand brain functioning and organization; molecular and cellular mechanisms underlying Parkinson's disease; maternal adversity and early life stress-on-stress response systems in the brain and in the immune system; and host/pathogen interactions at the cellular and molecular level.
- Fluorescence microscopy,
- Confocal microscopy,
- Spinning disk confocal microscopy,
- Total Internal Reflection Fluorescence (TIRF) microscopy,
- Multiphoton Microscopy,
- Structured illumination (Apotome)
- Optical sectioning,
- Transmission Electron Microscopy (TEM),
- Scanning Electron Microscopy (SEM),
- Patch clamping for electrophysiology,
- Micro-injection,
- Flow cytometry,
- Cell sorter,
- Gel imaging,
- Image analysis,
- Cryostat,
- Microtome,
- Ultramicrotome,
- Centrifuge,
- Autoclave,
- Polymerase Chain Reaction (PCR),
- High Performance Liquid Chromatography (HPLC)
- Education
- Healthcare and social services
- Life sciences, pharmaceuticals and medical equipment
Specialized labs and equipment
Equipment |
Function |
---|---|
BD FACSAria III |
Flow cytometry cell sorter |
BD LSRFortessa |
Flow cytometry cell analyzer |
Quorum Wave FX spinning disk microscope |
Live cell confocal imaging |
Quorum TIRF microscope |
Total Internal Reflection Fluorescence (TIRF) imaging |
Olympus Multiphoton Microscope |
Multiphoton Microscopy |
Zeiss ApoTome microscope |
Optical sectioning |
Volocity |
Image analysis software |
Imaris |
Image analysis software |
Neurolucida |
Neuroscience software |
Hitachi H-7500 TEM |
Transmission Electron Microscopy(TEM) |
Hitachi S530 SEM |
Scanning Electron Microscopy (SEM) |
Bio-Rad PharosFX |
Fluorescence gel imaging |
Bio-Rad ChemiDoc XRS+ |
Gel imaging |
PTC-200 Thermal Cycler |
Polymerase Chain Reaction (PCR) |
Waters HPLC |
High-Performance Liquid Chromatography (HPLC) |