Neurobiology research on stress, using various molecular, cellular and neurophysiological techniques.
The Centre for the Neurobiology of Stress (CNS) is a $10-million state-of-the-art facility. The centre tackles a series of critical areas: long-term memory and consolidation; the role of stress in natural population; maternal effects and maternal programming through epigenetic changes; neuroprotective roles of heat shock (stress) proteins; neurobiology and behaviour using fear, addiction, and other paradigms to understand brain functioning and organization; molecular and cellular mechanisms underlying Parkinson's disease; maternal adversity and early life stress-on-stress response systems in the brain and in the immune system; and host/pathogen interactions at the cellular and molecular level.
- Fluorescence microscopy
- Confocal microscopy
- Spinning disk confocal microscopy
- Total Internal Reflection Fluorescence (TIRF) microscopy
- Multiphoton Microscopy
- Structured illumination (Apotome)
- Optical sectioning
- Transmission Electron Microscopy (TEM)
- Scanning Electron Microscopy (SEM)
- Patch clamping for electrophysiology
- Micro-injection
- Flow cytometry
- Cell sorting
- Gel imaging
- Image analysis
- Cryostat
- Microtome
- Ultramicrotome
- Centrifuge
- Autoclave
- Polymerase Chain Reaction (PCR)
- High Performance Liquid Chromatography (HPLC)
- Education
- Healthcare and social services
- Life sciences, pharmaceuticals and medical equipment
Specialized labs and equipment
Equipment | Function |
---|---|
BD FACSAria III | Flow cytometry cell sorter |
BD LSRFortessa | Flow cytometry cell analyzer |
Quorum Wave FX spinning disk microscope | Live cell confocal imaging |
Quorum TIRF microscope | Total Internal Reflection Fluorescence (TIRF) imaging |
Olympus Multiphoton Microscope | Multiphoton Microscopy |
Zeiss ApoTome microscope | Optical sectioning |
Volocity | Image analysis software |
Imaris | Image analysis software |
Neurolucida | Neuroscience software |
Hitachi H-7500 TEM | Transmission Electron Microscopy(TEM) |
Hitachi S530 SEM | Scanning Electron Microscopy (SEM) |
Bio-Rad PharosFX | Fluorescence gel imaging |
Bio-Rad ChemiDoc XRS+ | Gel imaging |
PTC-200 Thermal Cycler | Polymerase Chain Reaction (PCR) |
Waters HPLC | High-Performance Liquid Chromatography (HPLC) |