Microfluidics for healthcare and drug discovery

University of Victoria, Victoria, British Columbia
What the facility does

Design, fabrication and testing of microfluidic platforms for drug discovery and healthcare applications.

Areas of expertise

Dr. Elvira's research group develops microfluidic (lab-on-a-chip) platforms for drug discovery and healthcare applications. The Elvira laboratory has been designed to fabricate and use microfluidic devices with feature sizes on the order of tens of micrometres. The laboratory has state-of-the art Class 100 laminar flow hoods for work under particulate-free conditions, several different types of pumping mechanisms for liquid insertion into the microfluidic devices, powerful Nikon microscopes for analysis and testing, and high-speed cameras for visualization of on-chip experiments.

Research services

Design, testing, prototyping, analysis, computational modelling, surface modification

Sectors of application
  • Agriculture, animal science and food
  • Chemical industries
  • Life sciences, pharmaceuticals and medical equipment
  • Manufacturing and processing
EquipmentFunction
Laminar flow workstations

Laminar flow workstations with filtered air gas gun:

 

  • AirClean Systems AC648TLFC (2)
  •  Air Science Purair Flow-48 ISO5 (Class 100)
Plasma ovenDiener Electronic Zepto One plasma system
Nikon Ti2-U microscopeNikon Ti2-U inverted microscope with phase contrast and 2x, 10x, 20x and 40x long working distance objective lenses
Nikon stereomicroscopeNikon SMZ1270 stereomicroscope with 22 mm field of view and an LED ring illuminator
Lipid preparation facility
  • Avanti extruder set with heating block
  • Gilson P2L, P20, P200 and P1000 pipettes
  • Fisher Scientific vortex mixer
Syringe pumpsWorld Precision Instruments Aladdin programmable syringe pumps (4)
Precision syringe pumpsCetoni neMESYS Low Pressure 290N syringe pumps with QmixELEMENTS control software (5)
Pressure pumpsElvesys OB1 pressure controllers with three 0-2000 mbar channels, one 0-8000 mbar channel and digital flow sensors
CameraTeledyne DALSA Genie Nano C1280
High-speed cameraPhantom VEO 710L high speed camera
High-speed cameraMikrotron MotionBLITZ EoSens Cube7 high-speed camera
High-speed camera for fluorescence imagingORCA-Flash4.0 V3 sCMOS camera with 82% high quantum efficiency
Nikon Ti2-E microscopeNikon Ti2-E inverted motorized microscope with perfect focus system, and 2x, 10x, 20x and 40x long working distance objective lenses, motorized epifluorescence turret and a motorized stage
Fluorescence light sourcesSolis cold white and 365 nm LED light sources with a variety of filter cubes
OvenFisher Scientific Isotemp gravity convection oven
Spin coaterLaurell Technologies WS-650Mz-23NPPB spin coater
TitleURL
Microfluidics in Health Care and Drug Discovery: Large-scale potential from small-scale chipshttps://www.uvic.ca/research/centres/biomedical/members/profiles/elvira-katherine.php
Dr. Elvira’s Canada Research Chair profilehttp://www.chairs-chaires.gc.ca/chairholders-titulaires/profile-eng.aspx?profileId=3903
Video about Dr. Elvira’s researchhttps://www.youtube.com/watch?v=WTBsPIXS6aU