Biorepository of human samples for research on cardiovascular and metabolic diseases.
IMPART Biobank is the only cardiovascular biobank in Atlantic Canada with expertise in inflammatory and metabolic diseases, specifically cardiovascular diseases, obesity, and diabetes. Our interests are in biomarker discovery, diagnostics and improving patient outcomes.
IMPART is a biorepository of samples for research purposes serving academic labs at Dalhousie University and affiliated institutions. The Biobank is a biospecimen sourcing partner for researchers worldwide, where we receive, store, processes, and/or disseminate biospecimens, their derivatives, and relevant data. We collect, process and store detailed, annotated human heart samples, serum, plasma and red blood cells from volunteer participants undergoing cardiac surgery, with a collection of over 300 patient samples.
The facility is in close proximity to DMNB research labs, and the Saint John Regional Hospital’s operating rooms that facilitate quick tissue collections, timely processing and storage of human samples. We offer high quality samples in various formats – fixed or frozen.
- Access to high-quality tissue samples in various formats (frozen and fixed)
- Access to complete medical record and post-surgical outcomes
- Access to super resolution microscopes, high-throughput multiplex assays (bioplex)
- Access to translational medicine, biotechnology and medical innovation consulting
- Education
- Healthcare and social services
- Life sciences, pharmaceuticals and medical equipment
Specialized labs and equipment
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Equipment |
Function |
|---|---|
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Tissue samples:
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Available for sharing with collaborators |
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Eppendorf -80 oC freezers |
Long term storage of human tissue samples |
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Bio-Plex Immunoassay System |
High-throughput protein quantification |
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Ella Multiplex System |
Single analyte and multiplex protein quantification |
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Cell culture incubators |
For human cell culturing |
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Cell culture hoods |
For tissue dissections and cell culturing activities |
Private and public sector research partners
- Servier Canada
- Pfizer Canada
- Medtronic Canada
- Cloud DX
- ProtoKinetix
- Breathe BioMedical
- Pivotal Health Solutions
Additional information
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Title |
Hyperlink |
|---|---|
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Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes |
https://www.sciencedirect.com/science/article/abs/pii/S1388198116302414 |
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Impact of Obesity on Postoperative Outcomes following cardiac Surgery (The OPOS study): rationale and design of an investigator-initiated prospective study |
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Changes in circulating monocyte subsets (CD16 expression) and neutrophil-to-lymphocyte ratio observed in patients undergoing cardiac surgery |
https://www.frontiersin.org/articles/10.3389/fcvm.2017.00012/full |
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Validation of optimal reference genes for quantitative real time PCR in muscle and adipose tissue for obesity and diabetes research |
|
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Lysophosphatidic acid receptor mRNA levels in heart and white adipose tissue are associated with obesity in mice and humans |
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0189402 |
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Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery |
https://link.springer.com/article/10.1186/s12967-019-02162-5 |
|
Serum GDF15, a promising biomarker in obese patients undergoing heart surgery |
https://www.frontiersin.org/articles/10.3389/fcvm.2020.00103/full |
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Adverse outcomes in obese cardiac surgery patients correlates with altered branched-chain amino acid catabolism in adipose tissue and heart |
https://www.frontiersin.org/articles/10.3389/fendo.2020.00534/full |