Small Animal Imaging Labs Platform of the Research Institute of the MUHC

McGill University Health Centre, Montréal, Québec
What the facility does

A comprehensive technology suite for non-invasive imaging of animal models to create holistic pictures of diseases.

Area(s) of Expertise

The Small Animal Imaging Labs (SAIL) Platform is a world-class centre designed to support the research activities of biomedical investigators.  SAIL provides a comprehensive suite of imaging modalities, including Magnetic Resonance Imaging (MRI) and spectroscopy (MRS), Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT), Computed Tomography (CT), optical imaging (bioluminescence/fluorescence), and autoradiography. Dedicated housing is available for mice and rats undergoing longitudinal imaging studies. Ancillary facilities and resources of the SAIL are devoted to image processing and analysis, animal surgery, and radiochemistry. We provide expertise in planning in vivo imaging studies, consultation and training.

Research Services

Magnetic resonance imaging, including  high-resolution structural, functional and molecular in vivo and ex vivo imaging, spectroscopy MRS, nuclear medicine imaging, including multimodality scanning; optical imaging, including high-sensitivity optical molecular imaging (bioluminescence and fluorescence), and co-registration with digital X-rays; autoradiography; radiochemistry; quantitative assessment of gait parameters; and a surgical suite, project design, extended assistance, dedicated housing, consultation and training 

Sectors of Application
  • Life sciences, pharmaceuticals and medical equipment

Name of specialized lab

Name of equipment in use

Description of function

Small Animal Imaging Labs

Bruker 7T MRI

High-resolution imaging of structural, functional, and molecular in vivo and ex vivo.

 

Bruker In-Vivo Extreme

High-sensitivity optical molecular imaging (bioluminescence and fluorescence) along with digital X-rays.

 

Mediso nanoScan SPECT/CT/PET

Tri-modality SPECT/CT/PET scanner allows for functional and molecular imaging using radiotracers.

 

Biospace Lab BetaIMAGER ™

Rapid, high-resolution, quantitative autoradiography. With ultra-low energy β-emitting tritium for great resolution.

 

GE Typhoon FLA 9500

Robust and versatile laser scanner for autoradiography studies (using storage phosphor screens).

 

CatWalk XT

A comprehensive free-walking gait analysis system for quantitative assessment of up to 35 gait parameters.

 

Leica CM1950 cryostat

Well-suited for generation of high- quality frozen tissue sections.

 

  • McGill Uniersity
  • Institut de recherches cliniques de Montréal (IRCM)
  • Centre de recherche du Centre hospitalier de l’Université de Montréal (CR CHUM)
  • Biospective Inc.