Characterization of biopolymers and soft materials
The optical trapping laboratory specializes in the mechanical characterization of individual molecules and microscale materials. Expertise ranges from single-molecule measurements to microrheology. The laboratory houses state-of-the-art instrumentation, including a centrifuge force microscope and optical trapping instruments, one a dynamic holographic optical tweezers instrument useful for characterizing soft materials (such as gels and matrices) that exhibit 2- and 3-dimensional microscale heterogeneity. In characterizing the growth of materials, our expertise includes monitoring the development of viscoelastic heterogeneity at high bandwidth (>1 kHz) over time scales from seconds to hours. The comprehensive wet lab neighbouring the optical tweezers instrumentation means that we can prepare and characterize biological and chemical samples in-house.
Mechanical characterization of soft materials at the single-molecule and microscale levels.
- Agriculture, animal science and food
- Clean technology
- Life sciences, pharmaceuticals and medical equipment
- Manufacturing and processing
Specialized labs and equipment
Specialized lab |
Equipment |
Function |
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Optical trapping laboratory |
Dynamic holographic optical tweezers |
Soft materials microrheology; monitoring spatially resolved development of viscoelasticity at the microscale |
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Optical tweezers |
Single-molecule characterization, microrheology |
High-throughput single-molecule manipulation laboratory | Centrifuge force microscope | Force-dependent enzymatic cleavage, ligand-receptor interactions |
Molecular biology laboratory |
Cell culture facilities |
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Microscopy facilities |
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Fast Protein Liquid Chromatography (FPLC) |
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UV-Vis Spectrophotometer |
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Fluorescence Plate Reader |
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Thermocycler |
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Gel electrophoresis and blotting |
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Close access to many other characterization facilities |
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Additional information
Title |
URL |
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Video showcasing our CFI-funded infrastructure-The age-old collagen question – Nancy Forde, SFU |