Research on biological mechanisms of disease and the development of new treatments.
Unity Health Toronto's Research Core Facilities has created an operating model of extensive shared-facility support for basic science research in the Keenan Research Centre. These facilities offer the latest equipment and techniques, in addition to professional training and management. By reducing duplication and increasing usage, the facilities offer significant savings, creating a critical mass where cutting-edge equipment and techniques are available to the team’s scientists.
The Research Core Facilities are spread over four floors and includes both common and specialized facilities, such as Flow Cytometry, Molecular Biology/Genomics, Histology, Imaging, Cell Culture, and Microfabrication. Each has a core coordinator whose primary role is to train users and provide technical expertise in the design and execution of scientific experiments. In addition, a state-of-the-art vivarium is available, providing training and assistance and adhering to the latest guidelines and regulations.
- Flow Cytometry Core
- Histology Core
- Genomics and Molecular Biology Core
- Bioimaging Core
- Molecular Pathology Core specialty service
- Research Vivarium
- Tissue Bank
- Microfabrication Core
- 3D printing
- Education
- Life sciences, pharmaceuticals and medical equipment
Specialized labs and equipment
Specialized lab | Equipment |
---|---|
Flow Cytometry | MACSQuant analyzers |
FACSAria III Cell Sorter | |
BD FACSCalibur 1 Flow Cytometer | |
BD Fortessa X20 Cell Sorter | |
Celigo platform | |
Molecular Devices ImageXpress Micro High-Content Imaging System | |
Beckman Coulter CytoFLEX-LX Flow Cytometer | |
SP6800 Spectral Cytometer | |
Miltenyi Biotec AutoMACS Automated Cell Separation System | |
Beckman Coulter Vi-CELL XR Cell Viability Analyzer | |
Histology | Leica Biosystems PEGASUS Tissue Processor |
Leica Biosystems TP1020 Automatic Tissue Processor | |
Leica Biosystems HistoCore Arcadia Embedding Centre | |
Leica Autostainer XL automated slide stainer | |
Epredia PrintMate AS Cassette Printer | |
Epredia Cytospin 4 Cytocentrifuge | |
Bio SB TintoRetriever Pressure Cooker | |
Paraffin Block Trimmer | |
Leica Biosystems CM3050 S Cryostat | |
Leica Biosystems RM2145 Rotary Microtome | |
Leica Biosystems RM2235 Rotary Microtome | |
Leica Biosystems HistoCore BIOCUT Rotary Microtome | |
Leica Biosystems VT1000 S vibrating blade microtome | |
Epredia SlideMate AS Slide Printer | |
ACDBio HybEZ II Hybridization Oven | |
Molecular Biology | Applied Biosystems ViiA 7 Real-Time PCR System |
Applied Biosystems StepOnePlus Real-Time PCR System | |
Applied Biosystems Veriti Thermal Cycler | |
NanoString nCounter Pro Analysis System | |
Agilent 2100 Bioanalyzer system | |
Captair RNA/DNA Rolling Clean Hood | |
Eppendorf MasterCycler Gradient Thermocycler | |
Bioimaging | ZEISS LSM 900 Confocal Microscope with Airyscan |
Quorum Spinning Disc confocal microscopy system | |
Olympus BX50 Upright Fluorescence Microscope | |
ZEISS Widefield Deconvolution Microscope | |
ZEISS Celldiscoverer 7 imaging platform | |
Agilent BioTek Cytation 5 Cell Imaging Multimode Reader | |
Agilent BioTek BioSpa Live Cell Analysis System | |
Nikon A1R Multiphoton Inverted Microscope | |
Analysis software (Halo, Imaris, ZEN, BioTek Gen5, MetaMorph, Kuant, QuPath) | |
iTHERA MSOT software | |
Heidelberg SPECTRALIS (HRA + OCT) Imaging Platform | |
Small Animal High Performance micro-CT (µCT ) scanner | |
Microfabrication and 3D printing | Class 10,000 (ISO 7) cleanroom |
NxQ4006 Mask Alignment System | |
Laurell WS-650 Spin Coaters | |
Torrey Pines HS40 Hot Plates | |
DMO MicroWriter ML3 Lithography System | |
Bruker Contour GT-K Optical Profilometer | |
Expanded Plasma Cleaner | |
Markforged Mark Two 3D Printer | |
CO2 laser cutter | |
ProFluidics 285D 3D Printer | |
CAD PC workstation | |
Spectradyne nCS2 Nanoparticle Analyzer | |
Beckman Coulter Multisizer 4e Coulter Counter Particle Sizer | |
Shimadzu UV-3600 UV-VIS-NIR Spectrophotometer | |
Shimadzu RF-5301PC Spectrofluorophotometer | |
Malvern Panalytical Archimedes Particle Metrology System | |
Malvern Panalytical ZetasizerUltra (Red Label) Light Scattering System |
Private and public sector research partners
- University of Toronto
- Toronto Metropolitan University
- Institute for Biomedical Engineering and Science Technology (iBEST)
Additional information
Title | URL |
---|---|
Research Facilities Business Management System (RFBMS) | www.rfbms.com |