Research Core Facilities

Unity Health Toronto, Toronto, Ontario
What the facility does

Research on biological mechanisms of disease and the development of new treatments.

Areas of expertise

Unity Health Toronto's Research Core Facilities has created an operating model of extensive shared-facility support for basic science research in the Keenan Research Centre. These facilities offer the latest equipment and techniques, in addition to professional training and management. By reducing duplication and increasing usage, the facilities offer significant savings, creating a critical mass where cutting-edge equipment and techniques are available to the team’s scientists. 

The Research Core Facilities are spread over four floors and includes both common and specialized facilities, such as Flow Cytometry, Molecular Biology/Genomics, Histology, Imaging, Cell Culture, and Microfabrication. Each has a core coordinator whose primary role is to train users and provide technical expertise in the design and execution of scientific experiments. In addition, a state-of-the-art vivarium is available, providing training and assistance and adhering to the latest guidelines and regulations.

Research services
  • Flow Cytometry Core
  • Histology Core
  • Genomics and Molecular Biology Core
  • Bioimaging Core
  • Molecular Pathology Core specialty service
  • Research Vivarium
  • Tissue Bank
  • Microfabrication Core
  • 3D printing
Sectors of application
  • Education
  • Life sciences, pharmaceuticals and medical equipment
Specialized labEquipment
Flow CytometryMACSQuant analyzers
 FACSAria III Cell Sorter
 BD FACSCalibur 1 Flow Cytometer
 BD Fortessa X20 Cell Sorter
 Celigo platform
 Molecular Devices ImageXpress Micro High-Content Imaging System
 Beckman Coulter CytoFLEX-LX Flow Cytometer
 SP6800 Spectral Cytometer
 Miltenyi Biotec AutoMACS Automated Cell Separation System
 Beckman Coulter Vi-CELL XR Cell Viability Analyzer
HistologyLeica Biosystems PEGASUS Tissue Processor
 Leica Biosystems TP1020 Automatic Tissue Processor
 Leica Biosystems HistoCore Arcadia Embedding Centre
 Leica Autostainer XL automated slide stainer
 Epredia PrintMate AS Cassette Printer
 Epredia Cytospin 4 Cytocentrifuge
 Bio SB TintoRetriever Pressure Cooker
 Paraffin Block Trimmer
 Leica Biosystems CM3050 S Cryostat
 Leica Biosystems RM2145 Rotary Microtome
 Leica Biosystems RM2235 Rotary Microtome
 Leica Biosystems HistoCore BIOCUT Rotary Microtome
 Leica Biosystems VT1000 S vibrating blade microtome
 Epredia SlideMate AS Slide Printer
 ACDBio HybEZ II Hybridization Oven
Molecular BiologyApplied Biosystems ViiA 7 Real-Time PCR System
 Applied Biosystems StepOnePlus Real-Time PCR System
 Applied Biosystems Veriti Thermal Cycler
 NanoString nCounter Pro Analysis System
 Agilent 2100 Bioanalyzer system
 Captair RNA/DNA Rolling Clean Hood
 Eppendorf MasterCycler Gradient Thermocycler
BioimagingZEISS LSM 900 Confocal Microscope with Airyscan
 Quorum Spinning Disc confocal microscopy system
 Olympus BX50 Upright Fluorescence Microscope
 ZEISS Widefield Deconvolution Microscope
 ZEISS Celldiscoverer 7 imaging platform
 Agilent BioTek Cytation 5 Cell Imaging Multimode Reader
 Agilent BioTek BioSpa Live Cell Analysis System
 Nikon A1R Multiphoton Inverted Microscope
 Analysis software (Halo, Imaris, ZEN, BioTek Gen5, MetaMorph, Kuant, QuPath)
 iTHERA MSOT software
 Heidelberg SPECTRALIS (HRA + OCT) Imaging Platform
 Small Animal High Performance micro-CT (µCT ) scanner
Microfabrication and 3D printingClass 10,000 (ISO 7) cleanroom
 NxQ4006 Mask Alignment System
 Laurell WS-650 Spin Coaters
 Torrey Pines HS40 Hot Plates
 DMO MicroWriter ML3 Lithography System
 Bruker Contour GT-K Optical Profilometer
 Expanded Plasma Cleaner
 Markforged Mark Two 3D Printer
 CO2 laser cutter
 ProFluidics 285D 3D Printer
 CAD PC workstation
 Spectradyne nCS2 Nanoparticle Analyzer
 Beckman Coulter Multisizer 4e Coulter Counter Particle Sizer
 Shimadzu UV-3600 UV-VIS-NIR Spectrophotometer
 Shimadzu RF-5301PC Spectrofluorophotometer
 Malvern Panalytical Archimedes Particle Metrology System
 Malvern Panalytical ZetasizerUltra (Red Label) Light Scattering System
  • University of Toronto
  • Toronto Metropolitan University
  • Institute for Biomedical Engineering and Science Technology (iBEST)
TitleURL
Research Facilities Business Management System (RFBMS)www.rfbms.com