Development of molecular diagnostics and therapeutics for cancer
The Centre for Pharmaceutical Oncology aims to bridge the gap between fundamental discoveries in cancer biology and first-in-humans clinical trials of new diagnostics and therapeutics for cancer by providing expertise in pharmaceutical science. Areas of expertise include: identification of molecular targets on tumours, point-of-care molecular diagnostics, nanoparticle drug delivery systems, radiopharmaceutical synthesis and characterization, molecular imaging (SPECT and PET), radioimmunotherapy, experimental therapeutics, pharmaceutical formulation, radiation dosimetry, polymer chemistry, antibody-based diagnostics and therapeutics. The Centre promotes collaborations between basic cancer biologists, pharmaceutical scientists and clinical oncologists to improve the outcomes of cancer patients.
- Molecular target identification for design of diagnostics and therapeutics for cancer.
- Design, synthesis and characterization of nanoparticle drug delivery systems for cancer.
- Engineering of point-of-care molecular diagnostics for cancer.
- Synthesis and characterization of radiopharmaceuticals for cancer imaging and therapy.
- Pharmaceutical polymer synthesis and characterization for cancer drug delivery.
- Life sciences, pharmaceuticals and medical equipment
Specialized Labs and Equipment
|
Specialized lab |
Equipment |
Function |
|
Centre for Pharmaceutical Oncology |
Mass spectrometer |
Molecular target identification |
|
|
HPLC system with diode array and ELS detectors |
Pharmaceutical characterization including nanoparticle drug delivery systems |
|
|
Multi-function plate reader with cell imaging capability |
Molecular target evaluation; Pharmaceutical development |
|
|
Flow cytometer |
Molecular target evaluation; Pharmaceutical development |
|
|
Liquid scintillation counter |
Pharmaceutical development |
|
|
Immunoelectrophoretic focusing (IEF) instrument |
Polymer characterization |
|
|
DLS plate reader |
Pharmaceutical characterization including nanoparticle drug delivery systems |
|
|
LC-MS chromatographic system |
Pharmaceutical development |
|
|
Refrigerated ultra-centrifuge |
Molecular diagnostics development |
|
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Fluorescence inverted microscope |
Molecular diagnostics development |
|
STTARR Innovation Centre |
Multimodality microSPECT/PET/CT imaging system |
Radiopharmaceutical development |