Pharmaceutical sciences, materials science, and engineering
Our laboratory is focused on the development and characterization of nanoparticles, medical devices and biomaterials for drug delivery applications. Our technology platforms are designed to be customizable to enhance drug solubility, targeted delivery, and improved therapeutic efficacy. We have the experience and knowledge to develop pharmaceutical formulations for small molecule drugs, proteins/peptides, and nucleic acids. We also have the infrastructure to provide in vitro and in vivo characterization, for example physico-chemical drug properties, tissue biocompatibility, and imaging.
Fabrication of pharmaceutical formulations (nanoparticles, biodegradable gels, films, solid dosage forms), pharmaceutical formulations for difficult-to-solubilize drugs, pharmaceutical formulations(fast-acting, sustained drug release, stimuli-responsive, targeted drug delivery), pharmaceutical formulations (intravenous, subcutaneous/intramuscular, intraperitoneal, transdermal, oral, intravaginal, rectal delivery), in vitro
characterization of pharmaceutical formulations (particle size, molecular weight, stability, drug release rates, cell toxicity studies), in vivo characterization of pharmaceutical formulations (rodent and rabbit models, tissue biocompatibility, pharmacokinetics studies, pharmacodynamics studies, rodent cancer models).
- Aerospace and satellites
- Agriculture, animal science and food
- Automotive
- Chemical industries
- Clean technology
- Construction (including building, civil engineering, specialty trades)
- Consumer durables
- Consumer non-durables
- Defence and security industries
- Energy
- Environmental technologies and related services
- Fisheries and aquaculture
- Forestry and forest-based industries
- Healthcare and social services
- Life sciences, pharmaceuticals and medical equipment
- Manufacturing and processing
- Mining, minerals and metals
- Ocean industries
- Utilities
Specialized labs and equipment
| Specialized facility | Equipment | Function |
|---|---|---|
| Advanced Microbicide Research and Analysis Facility (AMRAF) | Malvern Panalytical NanoSight NS300 NTA (Nanoparticle Tracking Analysis) | Nanoparticle size and concentration |
| Advanced Microbicide Research and Analysis Facility (AMRAF) |
Hot Melt injection molder
|
Fabrication of polymer medical devices from pre-designed aluminum molds |
| Advanced Microbicide Research and Analysis Facility (AMRAF) |
SPEX 6770 Freezer/Mill
|
Cryogenic grinding and pulverizing of tough and/or temperature-sensitive samples |
| Advanced Microbicide Research and Analysis Facility (AMRAF) | Waters UHPLC System | Determination of the concentration of drug samples |
|
Biologics Evaluation Facility
|
Biological safety cabinet and tissue culture incubator | Performing in vitro cell studies, including cytotoxicity, cell targeting, and drug uptake |
| Biologics Evaluation Facility | EVOS™ FL AUTO fluorescent microscope | Imaging adherent and suspension cells using phase contrast or fluorescence |
Additional information
| Title | URL |
|---|---|
|
Canadian Researchers Have Designed a Tool for Preventing HIV in Women
|
https://www.chatelaine.com/health/hiv-prevention-women/ |
| Scientists Have Found a New Treatment for Chlamydia |
https://nypost.com/2019/02/06/scientists-have-found-a-new-treatment-for-chlamydia/
|
| 3D Printing Could Revolutionize HIV Prevention Drug Delivery |
|