Laboratory for Drug Delivery and Biomaterials

University of Waterloo, Kitchener, Ontario
What the facility does

Pharmaceutical sciences, materials science, and engineering

Areas of expertise

Our laboratory is focused on the development and characterization of nanoparticles, medical devices and biomaterials for drug delivery applications. Our technology platforms are designed to be customizable to enhance drug solubility, targeted delivery, and improved therapeutic efficacy. We have the experience and knowledge to develop pharmaceutical formulations for small molecule drugs, proteins/peptides, and nucleic acids. We also have the infrastructure to provide in vitro and in vivo characterization, for example physico-chemical drug properties, tissue biocompatibility, and imaging. 

Research services

Fabrication of pharmaceutical formulations (nanoparticles, biodegradable gels, films, solid dosage forms), pharmaceutical formulations for difficult-to-solubilize drugs, pharmaceutical formulations(fast-acting, sustained drug release, stimuli-responsive, targeted drug delivery), pharmaceutical formulations (intravenous, subcutaneous/intramuscular, intraperitoneal, transdermal, oral, intravaginal, rectal delivery), in vitro 
characterization of pharmaceutical formulations (particle size, molecular weight, stability, drug release rates, cell toxicity studies), in vivo characterization of pharmaceutical formulations (rodent and rabbit models, tissue biocompatibility, pharmacokinetics studies, pharmacodynamics studies, rodent cancer models).

Sectors of application
  • Aerospace and satellites
  • Agriculture, animal science and food
  • Automotive
  • Chemical industries
  • Clean technology
  • Construction (including building, civil engineering, specialty trades)
  • Consumer durables
  • Consumer non-durables
  • Defence and security industries
  • Energy
  • Environmental technologies and related services
  • Fisheries and aquaculture
  • Forestry and forest-based industries
  • Healthcare and social services
  • Life sciences, pharmaceuticals and medical equipment
  • Manufacturing and processing
  • Mining, minerals and metals
  • Ocean industries
  • Utilities
Specialized facility  Equipment Function
Advanced Microbicide Research and Analysis Facility (AMRAF) Malvern Panalytical NanoSight NS300 NTA (Nanoparticle Tracking Analysis) Nanoparticle size and concentration
Advanced Microbicide Research and Analysis Facility (AMRAF)

Hot Melt injection molder


Fabrication of polymer medical devices from pre-designed aluminum molds
Advanced Microbicide Research and Analysis Facility (AMRAF)

SPEX 6770 Freezer/Mill


Cryogenic grinding and pulverizing of tough and/or temperature-sensitive samples
Advanced Microbicide Research and Analysis Facility (AMRAF) Waters UHPLC System Determination of the concentration of drug samples

Biologics Evaluation Facility


Biological safety cabinet and tissue culture incubator Performing in vitro cell studies, including cytotoxicity, cell targeting, and drug uptake
Biologics Evaluation Facility EVOS™ FL AUTO fluorescent microscope Imaging adherent and suspension cells using phase contrast or fluorescence
Title URL

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