NanoRobotics Laboratory

École Polytechnique de Montréal, Montréal, Québec
What the facility does

Use of nanotechnology for robotic platforms aimed at tumour targeting and vascular system navigation tools

Area(s) of Expertise

The research team has developed unique expertise in the application of magnetic fields aimed at targeted delivery of cancer-treatment medication. Its expertise also encompasses related fields, namely the production of therapeutic vectors such as FeCo magnetic nanoparticles encapsulated in PLGO microparticles and liposomes loaded with medications attached to ultra-performing magnetotactic bacteria. The team has also developed expertise in complex robotic systems and specialized medical tools such as MRI navigation, magnetic catheters, magnetic monopole generators, imaging and image resetting technologies, manufacturing of microfluidic polymer circuits and realization of full in vivo procedures.

Research Services

Human-scale medical nuclear magnetic resonance imaging (NMRI) with varied imaging sequences for the head / back / legs, animal supply facility (mice, rats, rabbits, pigs) with an operating room, magnetosome and bacterial culture production laboratory, 3D nanomanufacturing of photosensitive polymers, CNC machining, optical microscopy with visible light, microfluidic and electronic circuit manufacturing

Sectors of Application
  • Life sciences, pharmaceuticals and medical equipment

Specialized lab

Equipment

Function

UNIM (NanoRobotic Medical Intervention Unit)

Siemens Magnetom Skyra 3T MRI system

Two-source, 64-receiver-channel RF transmission system and antenna assembly to cover the whole body

 

MRI/NMR console (Tecmag Redstone 0-128 MHz, 1 Tx, 4 Rx)

Programmable MRI console

 

VNA, SVG and SVA RT analysis system (National Instruments)

Test platform for RF antennae and microwave circuits up to 6GHz

 

 Kuka KR300 Quantec Ultra

Handling robot and transfer table

 

CIOS Alpha

X-ray and fluoroscopy (20cm*20cm)

 

EkoHeat 65kW/100kHz

Induction heating system with applicator ~20cm

 

MRI-compatible pulse oximeter

Vital signs monitoring

 

Animal supply facility

Equipped with cage racks (mice, rats, rabbits, pigs), biological safety cabinet, ventilated surgery table, MRI-compatible anaesthesia

NanoRobotics Laboratory

Optical microscope (Zeiss Axio Imager Z1 m)

 

Inspection microscope with all contrast options

 

Clean glove box (Terra Universal series 100)

Clean-handling enclosure

 

Binocular microscope (Zeiss Stemi)

Binocular inspection

 

Three power sources (Sorensen 200 A)

High-voltage source used to power electromagnets

 

3D magnetometer

Portable magnetic field measuring system

 

CNC milling machine (EMCO PC Mill 55)

Precision milling of small parts

 

Chemical fume hood

Protection against toxic fumes

 

Biological safety cabinet

Protection against contamination

 

Circuit board plotter (LPKF Protomat 92 s/II)

Printed circuit board fabrication

 

Hot press (LPKF MultiPress II)

Multi-layer printed circuit board fabrication

 

Magnet shaker (Labworks ET-139)

Vibration test bench

 

High-voltage source (Bertan 230 series)

Multi-purpose high-voltage source

 

Vacuum oven (Isotemp 281A)

Material annealing and degassing

 

Logic analysis system (Agilent 16702 B)

Digital signals validation

NanoFabrication

Multiphoton structuring device (LZH M3DL)

3D printer with 1um resolution

 

Three linear stages (Aerotech ABL1000)

Fast 3D positioning

 

Femtosecond laser (KMLabs Griffin-3W)

2PP writing system source

Cell culture laboratory

Two (2) 10L instrumented fermenters (Infors)

Microorganism culture

 

Instrumented 40L fermenter (Infors)

Microorganism culture

 

Inverted microscope with colour camera (Ziess Axiovert Z1)

Basic inspection microscope

 

Cooled centrifuge (Sorval RT+)

Solution concentration

 

Rotary evaporator (Buchi vacuum controller D850 Rotavap R215 heating bath D491)

Homogenizer (Polytron PT6100)

Solution concentration

 

Sonicator

Cleaning and cavitation

 

Precision balance (Scientech SA120)

Substance weight measuring

 

Deionized water (Milliport Milli-Q)

Ultra-pure water source

 

Mechanical shaker

Liquid mixer

 

Vortex (Genie-2)

Liquid mixer

 

pH meter (Orion 5 Stars)

pH measuring

 

Minicentrifuge (Accuspin Micro)

Solution concentration

 

Biological safety cabinet

Sterile environment work

 

Ultrasonic bath

Parts cleaning

Title URL

List of our main media coverage

http://wiki.polymtl.ca/nano/index.php/Press_Review