The Centre for Continuous Flow Synthesis makes it possible to convert batch processes into continuous flow processes to synthesize molecules of interest in a safe and efficient way.
Continuous flow chemistry is a revolutionary technique that facilitates organic molecule synthesis and analysis on both small and large scales. Although this technology is only gradually being accepted as the way of the future, it is an innovative, efficient and powerful approach for preparing molecules that traditionally involved multiple tedious and potentially dangerous steps. Unlike a conventional organic reaction, which is generally carried out in round-bottom flasks and batch reactors, continuous flow chemistry uses reactors made of tubes that enable chemicals to circulate continuously in solution throughout the reaction. Compared to conventional reactors, continuous flow reactors transfer heat and mass faster due to their compact dimensions and high surface-to-volume ratio. Reactions are therefore better controlled, creating a safer working environment. The use of continuous flow reactors also reduces reaction times and improves yields and selectivity. Therefore, continuous flow chemistry can be used to synthesize simple small-scale or industrial-scale target molecules as well as libraries of new molecules. This technology has been seriously evaluated by pharmaceutical and industrial R&D laboratories throughout the world for sustainable development, in particular because it offers numerous production advantages such as processes that are more efficient, safe, economical and environmentally friendly. The Centre for Continuous Flow Synthesis combines a variety of advanced continuous-flow instruments for the synthesis, purification and analysis of target molecules, all under the same roof. With the help of our highly skilled personnel, your batch processes can be converted into continuous flow streams, producing molecules of interest in a safe and effective way.
Synthesis, analysis, purification, green chemistry, catalysis, continuous flow
- Aerospace and satellites
- Agriculture, animal science and food
- Automotive
- Chemical industries
- Consumer durables
- Consumer non-durables
- Defence and security industries
- Education
- Life sciences, pharmaceuticals and medical equipment
- Manufacturing and processing
Specialized labs and equipment
Specialized lab | Equipment |
---|---|
ThalesNano H-Cube hydrogenation reactor | |
Voyager microwave stop-flow reactor | |
Uniqsis continuous flow reactors with automation and gas insertion modules | |
Vapourtec R1C, R2+ and R4 reactors equipped with cooling, automation and gas insertion modules | |
Syrris high efficiency Asia pumps | |
Zaiput advanced liquid-liquid and pressure separators | |
Luzchem photoreactors for continuous flow reactions using ultraviolet ionizing radiation | |
Customizable systems (with syringe pumps and various parts that can be combined and assembled by researchers) to mount unique and specialized devices for continuous flow processes | |
Regional Centre of NMR spectroscopy | Bruker ARX-400 NMR spectrometer for in situ microreactor reaction analysis and for batch sample analysis |
Regional Mass Spectrometry Centre
| Waters UPLC ion mobility quadrupole time-of-flight mass spectrometer to perform high-throughput analyses |
OmniCal ultra-low-temperature microcalorimeter for molecule safety assessments |