Medicinal chemistry laboratory, Sherbrooke Pharmacology Institute

Université de Sherbrooke, Sherbrooke, Québec
What the facility does

Medicinal chemistry, drug discovery, peptide chemistry, macrocycles

Area(s) of Expertise

The lab designs and optimizes small molecules as tools to understand (validate) the potential of new biological targets, as well as to discover new drugs. The lab has many interdisciplinary collaborations and with industry.

Research Services

Medicinal chemistry, structure-activity relationships, leads identification, leads optimization, targets validation, drug discovery, macrocycles

Sectors of Application
  • Chemical industries
  • Life sciences, pharmaceuticals and medical equipment

Equipment

Function

Preparative HPLC coupled to a mass spectrometer (MS-prep)

UPLC-MS

Peptide synthesizer

400 MHz NMR

UPLC-MS/MS

Parallel synthesis platform

High-throughput purification of active compounds

High-throughput compound analysis

Peptide synthesis

Small molecule analysis

Small molecule and metabolite quantification

Molecule library synthesis

  • Neomed
  • Immune Biosolutions
  • Elanco Animal Health
  • Bayer Healthcare