Research into network structure and function of the mammalian nervous system
Neural circuits composed of multiple interneuron cell types located in the central nervous system (CNS) are responsible for generating many simple rhythmic behaviours in mammals. The laboratory uses a molecular genetic approach to identify distinct populations of interneurons that comprise these circuits, anatomical techniques to investigate their network connectivity, and physiological/behavioural techniques to determine the specific function of these neural circuits during behaviour.
These studies provide key information regarding the development and function of neural circuits within the CNS, and may help to devise therapies aimed at enhancing function after brain/spinal cord injury.
Single-cell electrophysiology, immunohistochemistry, laser capture microdissection, fluorescent, bright field, confocal, two-photon microscopy
- Life sciences, pharmaceuticals and medical equipment
Specialized labs and equipment
|
Specialized lab |
Equipment |
Function |
|---|---|---|
|
Molecular Biology |
Laser capture microdissector |
Capture and analyze content of single cells within nervous system |
|
Electrophysiology |
Patch clamp recorder |
Record activity from single cells or population of cells within nervous system |
|
Anatomy |
Leica Fluorescent Microscope |
Analyze structure and connectivity of cells |
| Anatomy | Photon microscopes (2) | Analyze structure and connectivity of cells |
Additional information
|
Title |
URL |
|---|---|
|
Dr. Simon Gosgnach |
https://www.ualberta.ca/medicine/about/people/Simon-Gosgnach |