Research on genetic diversity using combined computational and experimental techniques with capacity for handling biological samples for genomic DNA extraction and basic manipulation, DNA sequencing and analysis.
Using an integrated approach combining computational and experimental comparative and functional genomics technologies, the Bioinformatics and Comparative Genomics Lab is interested in studying the mechanisms of inter- and intra-species genetic diversity and their contribution to the diversity of biological traits with a special interest in whole genome based genetic testing (trueness to type), currently focusing on grapevine and wine yeasts , but open to working with other species.
Genomics software available for: 1) Analysis of methylation data, cytogenetic data, exon prediction, identification of genes; 2) Access to databases: retrotransposon insertion polymorphism, Hermansky-Pudlak syndrome, comparative cellular and molecular biology of longevity; 3) whole genome sequencing based genetic testing (available for grapevine and wine yeasts); 4) analysis of transposable element profiles of genomes.
- Agriculture, animal science and food
- Life sciences, pharmaceuticals and medical equipment
Specialized labs and equipment
Equipment | Function |
---|---|
FALCOR software | Online tool for calculating mutation frequency and rate from various mutation assays in bacteria and yeast (Luria-Delbrück fluctuation analysis). |
Prot2Gene software | Precise exon prediction and mapping using protein sequences. |
Retrotransposon Insertion Polymorphism (dbRIP) | Database of human Retrotransposon Insertion Polymorphisms (RIPs) integrated into the human genome annotation data (UCSC Genome Browser, University of California, Santa Cruz). |
Additional information
Title | URL |
---|---|
Professor Ping Liang. | https://brocku.ca/mathematics-science/biology/directory/ping-liang/ |
dbRIP database. | https://dbrip.brocku.ca |
FALCOR software. | http://genomics.brocku.ca/FALCOR/ |
Prot2Gene software. | http://genomics.brocku.ca/prot2gene/ |