Separation science research on recombinant biotherapeutics, vaccines and biosimilars
The laboratory has expertise in separation sciences and analytical biotechnologies. Specifically, research and method development are performed to provide scientific guidance on protein based biologics used in drugs and pharmaceutical products. The laboratory is also proficient in the matter of biosimilars, glycoproteins and vaccines products.
The laboratory provides expertise in High-Performance Liquid Chromatography and Capillary Electrophoresis analytical applications through collaborative arrangements.
- Life sciences, pharmaceuticals and medical equipment
Specialized labs and equipment
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Equipment |
Function |
|---|---|
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Waters Alliance High Performance Liquid Chromatography (HPLC) systems |
HPLC system with PDA (Photodiode Array) and Fluorescence detector |
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SCIEX PA800 Plus Capillary Electrophoresis (CE) system
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CE systems are equipped with UV, PDA and Laser-induced Fluorescence detector |
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SCIEX CESI Plus* Capillary Electrophoresis system
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CESI Plus* can be coupled to MS system for mass detection |
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Bruker uTOF (micro Time of Flight) II Mass spectrometry system |
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Private and public sector research partners
European Directorate for Quality of Medicines Expert group 6
Additional information
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Title |
URL |
|---|---|
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Biologics and Genetic Therapies Directorate |
https://www.canada.ca/en/health-canada/corporate/about-health-canada/branches-agencies/health-produ… |
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Fast and highly selective determination of hemagglutinin content in quadrivalent influenza vaccine by reversed-phase high-performance liquid chromatography method. J Chromatrogr A. |
https://www.ncbi.nlm.nih.gov/pubmed/29122283
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NMR study of mutations of glycine-52 of the catalytic domain of diphtheria toxin. J Pharm Biomed Anal |
https://www.ncbi.nlm.nih.gov/pubmed/29216588
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Dodecylphosphocholine Micelles Induce Amyloid Formation of PrP Peptide via α-Helical Metastable Conformation. PLOS ONE
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168021
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