BioZone Mass Spectrometry Facility (BioZone MSF)

University of Toronto, Toronto, Ontario
What the facility does

Supports research programs with customized and high-quality mass spectrometry services for the analysis of biological and non-biological samples.

Areas of expertise

Modern mass spectrometers have exquisite accuracy, sensitivity, resolution, and range that allows for the precise identification of proteins, small molecules, and metabolites. The BioZone Mass Spectrometry Facility (BioZone MSF) uses the incredible power of this technique to address challenging problems in industrial and environmental biotechnology, health sciences, and biomedical research.

Through detailed, application-specific method development and expert advice on sample preparation and methodology, the BioZone MSF provides high-quality analytical data in support of small-molecule chemical analysis in biological and environmental samples, metabolic profiling, and proteomics, even for complex mixtures and challenging matrices.

While in-house applications focus on research in industrial and environmental biotechnology, the facility specializes in developing mass spectrometry methods for hard-to-analyze samples in a range of application areas, including biomedical and veterinary sciences.

Research services

The BioZone MSF provides high performance liquid chromatography / mass spectrometry and related services, such as small molecule analysis, metabolomics, proteomics and custom method development, for academic, institutional, and commercial clients.

Sectors of application
  • Chemical industries
  • Clean technology
  • Environmental technologies and related services
  • Forestry and forest-based industries
  • Life sciences, pharmaceuticals and medical equipment
EquipmentFunction
Thermo Scientific Q-Exactive Ultra High Mass Range (UHMR) Hybrid Quadrupole-Orbitrap Mass Spectrometry System with Ultra-High-Performance Liquid Chromatography (UHPLC)Perform small molecule mass spectrometry (MS), quantitative metabolomics and proteomics from complex mixtures.
Agilent (Varian) Saturn 2100T Gas Chromatography/Mass Spectrometry (GC/MS) systemPerform small molecule mass spectrometry (MS) on volatile small molecule samples.
Agilent 7000D Triple Quad Gas Chromatography/Mass Spectrometry (GC/MS) systemPerform small molecule mass spectrometry (MS) on volatile small molecule samples.
Thermo Scientific UltiMate 3000 Ultra-High-Performance Liquid Chromatography (UHPLC) systemPerform small molecule detection using Refractive Index (RI) and/or UV/Visible wavelengths.
  • Vale
  • Glencore Canada
  • Process Research ORTECH Inc.
  • Veolia
  • BP Canada Energy Group ULC
  • Alco Energy Canada
  • West Fraser
  • Bioindustrial Innovation Canada
  • Corteva Agriscience
  • Imperial Oil
  • DuPont
  • SiREM
  • Phycus Biotechnologies
  • Ardra
  • Liven Proteins