Proteomics and metabolomics analytical mass spectrometry
The UVic-Genome BC Proteomics Centre (PC) is the longest operating protein and metabolomics core facility in Canada, providing analytical mass spectrometry services to academic, industrial and government laboratories for over 30 years. The PC has performed proteomics and metabolomics services for more than 2,000 research projects in health, agriculture, energy, environment and forestry. The Centre’s technology development program supports service and collaborative research projects in the application and development of novel methods in the areas of biomarker identification and characterization, protein characterization, as well as bioinformatics. The Centre offers significant expertise in supporting custom projects that require novel solutions to answer our user’s research question.
- Untargeted quantitative proteomics (e.g. iTRAQ and Label-free, Data Independent Acquisition)
- Targeted quantitative proteomics providing absolute concentration
- Untargeted metabolomics detecting >5,000 metabolite features
- Targeted metabolomics using >30 metabolite class or pathway specific assays, for >1,100 metabolites
- Protein characterization including hydrogen-deuterium exchange, protein cross-linking, surface modifications, characterization of post-translational modifications
- Bioinformatics and statistical services to aid in experimental design, data interpretation and visualization
- Agriculture, animal science and food
- Chemical industries
- Energy
- Environmental technologies and related services
- Fisheries and aquaculture
- Forestry and forest-based industries
- Life sciences, pharmaceuticals and medical equipment
Specialized labs and equipment
Equipment |
Function |
---|---|
Agilent Triple Quadrupole Mass Spectrometers (6490/6495B) (4) |
Targeted (MRM) proteomics |
Thermo Scientific Orbitrap Mass Spectrometer (Velos pro and Fusion) |
|
Bruker Ultraflex III MALDI TOF/TOF Mass Spectrometer |
|
Tecan Liquid Handling System |
Automated sample processing |
Agilent Bravo Liquid Handling Platform |
Automated sample processing |
Biotage SYRO II Peptide Synthesizer |
High-throughput peptide synthesis |
Agilent Single Quadrupole and Liquid Chromatography Mass Spectrometer (LC/MS system) |
Peptide purification |